Jean-Christophe Marine obtained his PhD from the University of Liège, (Belgium, 1996), and was a Howard Hugues Medical Institute Fellow at the St Jude Children's Research Hospital (Memphis, USA, 1996-99). He was a Marie Curie Fellow at the European Institute of Oncology (IEO, Milan, Italy, 2000-2003).
He became a junior VIB Group leader in 2004 at the University of Ghent (Belgium) and moved his laboratory to the University of Leuven (KULeuven) in 2010 where he is now Professor, senior VIB group leader and Director of the VIB center for Cancer Biology. He received several national and international prizes, including the EMBO Young Investigator award in 2006, for his work on p53 modifiers.
His interests focus on the mechanisms by which cancer-specific non-mutational (i.e. epigenetic and (post-)transcriptional) events modulate tumor initiation, progression and therapy outcome.
Our laboratory has recently developed a growing interest in several aspects of melanoma biology, and in particular, in the identification of melanoma initiating cells and the mechanisms that contribute to early tumor development, emergence of inter- and intra-tumor heterogeneity and therapy resistance.